Postdoctoral Fellow at Georgia Institute of Technology with Dr. Joshua Weitz and Dr. Harold Kim.
Joint position in the School of Biology and the School of Physics.

Tae Lee

Contact Information

  • School of Biology
  • 310 Ferst Dr
  • Georgia Institute of Technology
  • Atlanta, GA 30332
  • USA

  • Office: 237 Cherry Emerson
  • Office Tel: +1 404 385 5474
  • E-mail: taejlee@gatech.edu
  • Lab Page

Curriculum Vitae

My CV can be found here.

Research Interests

Systems Biology, Synthetic Biology, Noise in gene expression, Gene Dosage Effect.

I am interested in applying synthetic biology and systems biology approaches to answer interesting biological questions. Using a combination of mathematical modeling and experiments, I studied gene regulatory networks that underlie the mammalian cell cycle during my Ph.D. Using a similar approach, I have also analyzed host-pathogen interactions between bacteria and mammalian cells.

Currently, I am interested in two lines of work: 1) cell-fate prediction and 2) gene dosage effect on gene expression. In the Weitz group, I will develop theoretical foundation on these works, and I will test these theories in the Kim lab.

Publications

Peer-reviewed Articles
  • Lee TJ, Yao G, Bennett DC, Nevins JR, You L (2010) Stochastic E2F Activation and Reconciliation of Phenomenological Cell-Cycle Models. PLoS Biol 8(9): e1000488
  • Lee TJ, Yao G, Nevins J, You L (2008) Sensing and integration of Erk and PI3K signals by Myc. PLoS Computational Biology 4:e10000013
  • Yao G, Lee TJ, Mori S, Nevins JR, You LC (2008) A Bistable Rb-E2F switch underlies the restriction point. Nature Cell Biology 10:476-U255
  • Bobkov, K.V. and Bowsher, J.E. and Greer, K.L. and Jaszczak, R.J. and Braun, K.E. and Lee, T.J., Phantom assessment of new acquisition geometries for breast pinhole SPECT imaging, IEEE Trans. Nucl. Sci. (USA), vol. 53 no. 3 (2006), pp. 1162 - 7

  • Book Chapters
  • T. Lee, L. You (2010) Modeling cell cycle processes: Cell cycle transition, principles of the restriction point. In Encyclopedia of Systems Biology, Eds. W. Dubitzky, O. Wolkenhauer, K.H. Cho, and H. Yokota. Springer Major Reference Works (In review)
  • T. Lee, D. Tu, C.M. Tan, and L. You (2007) Modeling cellular networks. In Systems Bioinformatics: An Engineering Case-Based Approach, Eds. G. Alterovitz & M. Ramoni. Chapter 6. Page 151-178 (Peer reviewed)
  • D. Tu, J. Lee, T. Ozdere, T. Lee, and L. You. (2007) Engineering gene circuits: foundations and applications. In Nanotechnology in Biology and Medicine: Methods, Devices and Applications, Ed. T. Vo-Dinh. CRC Press. Chapter 20. Page 363-380

  • Manuscripts in preparation
  • N. Elliott, T. Lee, L. You, F. Yuan (2010) Proliferation behavior of E. coli in Three-dimensional in-vitro tumor model (Under review in Integrative Biology)