Collective fate determination in bacterial viruses
For many bacterial viruses, the choice of whether to kill host cells or enter a latent state depends on the multiplicity of coinfection. We recently suggested a nonlinear basis for the finding that deterministic decisions can be reached, e.g., lysis or latency, depending on the cellular multiplicity of infection. The results were published in Biophysical Journal, Collective decision making in bacterial viruses.
Discussion of our findings can be found online:
- Nature Research Highlights, "Collective calm".
- Georgia Tech Press Release, To Kill or Not to Kill: Study Reveals How Co-infecting Viruses Coordinate to Determine a Bacterial Cell’s Fate
- Science Daily, various blogs, etc.